Termez is a southernmost city of Uzbekistan located on the right-hand bank of Amudariya river just at the border with Afghanistan.
It was there where in 329 BC Alexander the Great (of Macedon) crossed Oxus river (today’s Amudaria) on his chase after Bess – the traitor of Darius the 2rd Kadoman and usurper of power of Achemenid Persia. Alexander renamed, as he often did, the town after himself into "Alexandria Tarmita".
The town known from 1st millennium BC came to existence at the place of traditional river-crossing and has always played extremely important role in transporting goods and spreading knowledge, including religion, scientific and culture knowledge, from India into Central Asia and further up to China and Japan.